產品屬性：
產品名稱 | TC JL 37 |
規格 | 10 mg、50 mg |
貨號 | EY-01Y10782 |
Cas No.: 1258294-34-6
別名: N/A
化學名: N/A
分子式: C17H11ClF2N4O2
分子量: 376.74
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Potent inhibitor of tyrosine kinase 2 (TYK2, Ki = 1.6 nM). Shows some selectivity for TYK2 over JAK1/2/3. Inhibits IFNγ production in vivo in mice. Orally bioavailable.Liang et al (2013) Lead optimization of a 4-aminopyridine benzamide scaffold to identify potent, selective, and orally bioavailable TYK2 inhibitors. J.Med.Chem. 56 4521 PMID:23668484
特別提醒公司產品僅供科研使用
