產(chǎn)品屬性：
產(chǎn)品名稱 | Sumanirole maleate |
規(guī)格 | Free Sample (0.1-0.5 mg)、10mM*1mL in DMSO、5mg、25mg、50mg、100mg、200mg、500mg |
貨號(hào) | EY-01Y13737 |
Cas No.: 179386-44-8
別名: N/A
化學(xué)名: N/A
分子式: C15H17N3O5
分子量: 319.31
溶解度: DMSO: 50 mg/mL (156.59 mM); H2O: 10 mg/mL (31.32 mM)
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Sumanirole maleate(PNU 95666E; U95666E) is a highly selective D2 receptor full agonist with an ED50 of about 46 nM.IC50 value: 46 nM (EC50)Target: D2 receptorSumanirole was developed for the treatment of Parkinson's disease and restless leg syndrome. While it has never been approved for medical use. Sumanirole is a highly valuable tool compound for basic research to identify neurobiological mechanisms that are based on a dopamine D2-linked (vs. D1, D3, D4, and D5-linked) mechanism of action.[1]. Arthur G. Romero, et al. Synthesis of the Selective D2 Receptor Agonist PNU-95666E fromD-Phenylalanine Using a Sequential Oxidative CyclizationStrategy. J. Org. Chem. 1997, 62, 6582-6587
特別提醒公司產(chǎn)品僅供科研使用
