產(chǎn)品屬性：
產(chǎn)品名稱 | TM38837 |
規(guī)格 | 10mM*1 mL in DMSO、5mg、10mg、50mg、100mg |
貨號 | EY-01Y13809 |
Cas No.: 1253641-65-4
別名: N/A
化學(xué)名: N/A
分子式: C30H25Cl2F3N4OS
分子量: 617.51
溶解度: DMSO: 41.67 mg/mL (67.48 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
TM38837 is a peripheral selective cannabinoid receptor type 1 (CB1) receptor antagonist. TM38837 shows limited penetrance to the brain in order to minimize or prevent CNS adverse reactions, and preserves potential antiobesity effects. TM38837 reduces propensity for psychiatric side effects[1][2].[1]. Micale V, et al. The Cannabinoid CB1 Antagonist TM38837 With Limited Penetrance to the Brain Shows ReducedFear-Promoting Effects in Mice. Front Pharmacol. 2019 Mar 20;10:207.
[2]. Klumpers LE, et al. Peripheral selectivity of the novel cannabinoid receptor antagonist TM38837 in healthy subjects. Br J Clin Pharmacol. 2013 Dec;76(6):846-57.
特別提醒公司產(chǎn)品僅供科研使用
