產品屬性：
產品名稱 | SGC AAK1 1 |
規格 | 5 mg、25 mg |
貨號 | EY-01Y15220 |
Cas No.: 2247894-32-0
別名: N/A
化學名: N/A
分子式: C21H25N5O3S
分子量: 427.52
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Adaptor-associated protein kinase 1 (AAK1) and BMP-2-inducible protein kinase (BMP2K) inhibitor (IC50 values are 233 nM and 1.48 μM for AAK1 and BMP2K, respectively). Inhibits AAK1-dependent phosphorylation of AP2M1. Activates Wnt signaling.Agajanian et al (2018) AAK1 inhibits WNT signaling by promoting clathrin-mediated endocytosis of LRP6. View pre-publication manuscript.
特別提醒公司產品僅供科研使用
