產(chǎn)品屬性：
產(chǎn)品名稱 | ZLDI-8 |
規(guī)格 | 10 mM * 1 mL in DMSO、5mg、10mg、50mg、100mg |
貨號 | EY-01Y17661 |
Cas No.: 667880-38-8
別名: N/A
化學(xué)名: N/A
分子式: C??H??N?O?S
分子量: 433.52
溶解度: 62.5 mg/mL in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
ZLDI-8 is a Notch activating/cleaving enzyme ADAM-17 inhibitor and inhibits the cleavage of Notch protein. ZLDI-8 decreases the expression of pro-survival/anti-apoptosis and epithelial-mesenchymal transition (EMT) related proteins. ZLDI-8 is also a competitive and irreversible tyrosine phosphatase (Lyp) inhibitor with an IC50 of 31.6 μM and a Ki of 26.22 μM. ZLDI-8 inhibits the growth of MHCC97-H cells with an IC50 of 5.32?μM[1][2].
特別提醒公司產(chǎn)品僅供科研使用
