產(chǎn)品屬性：
產(chǎn)品名稱 | TAO Kinase inhibitor 1 |
規(guī)格 | 10mM*1mL in DMSO、1mg、5mg、10mg、25mg、50mg、100mg、200mg500mg、 |
貨號(hào) | EY-01Y17803 |
Cas No.: 850467-66-2
別名: N/A
化學(xué)名: N/A
分子式: C25H24N2O2
分子量: 384.47
溶解度: DMSO: 62.5 mg/mL (162.56 mM); H2O: < 0.1 mg/mL (insoluble)
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
TAO Kinase inhibitor 1 (compound 43) is a selective, ATP-competitive thousand-and-one amino acid kinases (TAOK) inhibitor with IC50s of 11 to 15 nM for TAOK1 and 2, respectively. TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death[1].TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death in centrosome amplified breast cancer cells[1].[1]. Koo CY, et al. Targeting TAO Kinases Using a New Inhibitor Compound Delays Mitosis and Induces Mitotic Cell Death in Centrosome Amplified Breast Cancer Cells. Mol Cancer Ther. 2017 Nov;16(11):2410-2421.
特別提醒公司產(chǎn)品僅供科研使用
