產品屬性：
產品名稱 | Lumisterol 3 |
規(guī)格 | 1 mg |
貨號 | EY-01Y21011 |
Cas No.: 1/7/5226
別名: N/A
化學名: N/A
分子式: C27H44O
分子量: 384.6
溶解度: Chloroform: slightly soluble,Methanol: slightly soluble
儲存條件: -80°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Lumisterol 3 (L3) is a photoisomer of previtamin D3 .1 It is formed by photoisomerization of previtamin D3 in the epidermis by prolonged UVB exposure and is metabolized by the cytochrome P450 (CYP) isoform CYP11A1 in a variety of tissues to several hydroxylated metabolites, including the active metabolites 20-hydroxy L3, 24-hydroxy L3, and 20,22-dihydroxy L3.2,31.Slominski, A.T., Chaiprasongsuk, A., Janjetovic, Z., et al.Photoprotective droperties of vitamin D and lumisterol hydroxyderivativesCell Biochem. Biophys.78(2)165-180(2020)
2.Holick, M.F.Photosynthesis of vitamin D in the skin: Effect of environmental and life-style variablesFed. Proc.46(5)1876-1882(1987)
3.Slominski, A.T., Kim, T.-K., Hobrath, J.V., et al.Characterization of a new pathway that activates lumisterol in vivo to biologically active hydroxylumisterolsSci. Rep.7(1)11434(2017)
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